PATHWAY ONE
UV Damage
Breaks down collagen and elastin. Wrinkles, sunspots, loss of elasticity.
4.8 from 15,240 reviews
Published clinical trial
4 US patents
Made in the USA
THE THREE PATHWAYS OF SKIN AGING
Your routine likely addresses two of three.
Sunscreen prevents UV damage. Antioxidants defend against free radicals. Supplamine® interrupts glycation.
PATHWAY TWO
Oxidative Stress
Free radicals damage cells. Dullness, uneven tone, premature aging.
PATHWAY THREE
Glycation
Explore a more personal approach, shaped around your unique needs.
How Supplamine® works
One technology. Two points in the pathway.
Glycation produces 3DG, a highly reactive molecule that goes on to bind and damage collagen. Supplamine® reduces how much 3DG forms, and neutralizes what is already present.
Sugar binds
Sugars attach to collagen and elastin.
Cross-links form
The bonds tie fibers together and stiffen them.
Structure alters
Collagen loses its flexibility.
Visible aging
Loss of firmness, sagging, deep lines.
Where Supplamine® interrupts it
Supplamine® · point one
Block formation
Intercepts the pathway before the reactive 3DG is released.
Supplamine® · point two
Neutralize the rest
Inactivates the 3DG already present in the skin.
8-week facial study · O-045
Results that keep building.
Measured at weeks 2, 4, 6 and 8. improving at every checkpoint.
+62.9%
Skin hydration at 8 weeks
+35.4%
Skin firmness at 8 weeks
−44.2%
Wrinkle reduction
−50.5%
Superficial facial lines
Before
After 28 days
Before
After 28 days
Before
After 28 days
Loved by our customers
What people report.
