Dermatologist Recommended Skin Care

Our breakthrough in skin science targets toxic sugars and inflammation – the root cause of skin aging.

Trust the science. See the results.

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Shop By Skin Concern

Neck and Chest

Dryness and Dehydration

Sensitivity and Redness

Fine Lines and Wrinkles

The Proof is in the Science

Supplamine® is proven in nine clinical trials to reduce the appearance of fine lines, wrinkles, sagging, and dryness in skin.  Formulated by scientists, tested and approved by dermatologists.

Trust the science.

Glycation: The Leading Cause of Skin Aging

Glycation occurs when sugar binds to proteins in the skin, such as collagen and elastin, causing them to collapse and form wrinkles.

MEG 21’s patented Supplamine® is clinically proven to prevent toxic sugar production and neutralize pre-existing harmful sugars, essentially stopping glycation in its tracks.

The Effects of Skin Glycation

Recommended by Skincare Professionals 

MEG 21 with Supplamine® products are on the cutting edge of skin therapy. They uniquely and effectively address glycation, one of the most overlooked processes of skin aging. They are a great preventive treatment for the long-term damaging effects of sugar.

–M. Elizabeth Briden, MD, FAAD

I am truly impressed with MEG 21 with Supplamine® Brightening Gel Cleanser. I honestly have never been a fan of gels…They make the skin tight and dry…when I’m doing a facial. Your gel cleanser cleaned
the skin so well and left the skin feeling clean and balanced, and my hands still felt perfectly hydrated even after a double cleanse.

— Julia Willenbring, Lead Esthetician at
Bernard’s Salon & Day Spa

MEG 21 with Supplamine® provides effective moisturization, as well as addresses skin firmness and reduces fine lines and wrinkles in as little as four weeks. For patients that undergo surgical procedures, MEG 21 provides improved wound healing, erythema reduction, and smoother skin texture. Even patients that are just looking for a daily moisturizer get benefits with constant use of MEG 21.

— Adrian Manjarrez-Cortez, MD
Board-Certified Plastic Surgeon

MEG 21 products are by far the best topical treatments for deep moisturizing and anti-aging effects that I have found…When I recommend MEG 21, I speak from both science and personal experience. The patented ingredient that sets MEG 21 apart is Supplamine®, which reverses glycation caused by dietary sugars…It makes skin supple—less wrinkled, less dry– less “hard.”

— Dr. Alice R. McKee, MD, PC, Medical Director of GLO Medspa and Laserderm Medspa

Regimens, FAQs, Ingredients

Discover anti-aging skincare tips, guides for creating the perfect regimen for your skin, and cutting-edge insight into the most effective cosmetic treatments so you can stay glowing!