Advanced Formula

Anti-Aging Face & Neck Moisturizing Cream

As we age, it’s not just our faces that show signs of wear and tear. Our necks and décolletage area can also look crepey, saggy, and lined. But with MEG 21’s Smooth Radiance Advanced Formula, you can help keep your skin looking its best at any age.

This light anti-aging cream is powered by patented Supplamine® and is clinically proven to reduce the appearance of lines, wrinkles, crepey skin, and UV damage within 28 days. It’s perfect for firming and repairing skin and is nonirritating for those with sensitive skin. Plus, the dose-dispensed airless pump ensures extra purity.

Order your 1.7 oz jar today to see the difference for yourself!


  • Visible, measurable results in mature skin in 30 days or less. Diminishes the visible signs of aging skin for all ages. Just one pump from dosed, airless jar twice a day does it!
  • Repairs, firms, lifts and tones crepey, sagging, wrinkled mature skin.  Ideal for use on face, neck, throat, jowls and crinkly lips. Evens skin tone and gently lightens freckles and age spots over time.
  • Exclusively contains patented Supplamine, a unique, powerful skin anti-aging ingredient, proven highly effective in 9 independent, dermatologist-conducted clinical trials with over 125 subjects, 40 to 60 years of age. Also contains natural amino acids to positively effect collagen and elastin in skin. 
  • Formulated by a team of scientists conducting breakthrough medical research and licensed from a major medical center in Philadelphia.
  • Endorsed, recommended, and sold exclusively by dermatologists, medi-spas and plastic surgeons to their patients for the first 10 years, and one of the first skin care lines invited by Amazon to launch into its Professional Beauty.
  • A percentage of all sales are returned to the medical center in Philadelphia for continued medical research.
How to Use

Apply 2 pumps of MEG 21 Advanced Formula twice daily to freshly cleansed and toned throat, neck and chest. Apply with gentle upward strokes, beginning with the area just below the ear lobes, then to the chin, throat and chest. Gentle enough for the face. When going outside use over MEG 21 Anti-Oxidant Boost. Follow with a sunscreen in the morning.

To dispense, lift off, without twisting cap; gently press down on white disc using two thumbs to pump. When using the airless jar for the first time, you might need to “prime” by slowly pressing down on the white disc several times. This process of “priming” will activate the vacuum pump system.

Key Ingredients
  • Supplamine: Patented ingredient to intercept and reverse glycation, inflammation and metabolic oxidation caused by 3DG sugars in the skin
  • Jojoba Oil  – Emolliency similar to natural oil structure produced by the skin
  • Evening Primrose  – Clears pathway to allow barrier penetration
  • Squalene – Hydrates by increasing natural moisture within the skin
  • Vitamin E   – Healing antioxidant
  • Aloe  – Natural anti-irritant to reduce inflammation
  • Shea Butter – natural antioxidant rich emollient
  • Green Tea – potent antioxidant and anti-inflammatory

Clinical Trial Results

Rigorous scientific research provides the proof and efficacy of our patented, ingredient, Supplamine, found only in MEG 21 products.

Many trials and tests of MEG 21 products, including double-blind studies and those using placebos, comparative products and consumer insights, have been mounted by independent laboratories.

Toxic Sugars detected in skin as we age:

  • 23 Year Old 15% 15%
  • 49 Year Old 35% 35%
  • 69 Year Old 75% 75%
Increase in skin health after 4 weeks use:
  • Firmness by Ballistomoter 22% 22%
  • Moisture by Impedence Meter 42% 42%
  • Smoothness by Expert Grader 43% 43%
  • Smoothness by Image Analysis 37% 37%



Refine & Refresh Moisturizing Toner

Refreshes and hydrates after cleansing

Smooth Radiance Face Treatment

Help reduce the appearance of fine lines and wrinkles