The Science

MEG 21 products contain our patented Supplamine, the only skin-care ingredient with clinically proven, toxic sugar-blocking technology to reverse the appearance of aging skin within 28 days.

Real Science, better skin

  • During intensive medical research at a world-renowned medical center in Philadelphia, a ground-breaking treatment to reduce the signs of aging was discovered when the scientists uncovered an enzyme called F3K, which furthers the production of toxic sugars in the skin. That process causes serious inflammation and glycation, two distinct events that contribute to skin aging.
  • But glycation and inflammation are not limited to disease — they happen in everyone’s body and skin and are exacerbated by toxic sugars from our diets and normal metabolism.

  • Our research scientists discovered a compound that intervenes in the production and availability of toxic sugars – a leading cause of inflammation, skin aging and wrinkling – in skin.

Supplamine: Results in Less Glycation

  • Glycation, the process by which sugar molecules bind to proteins and lipids, is implicated in many age related diseases.
  • Glycation and inflammation from toxic sugars are major factors in the aging of skin, as the collagen that maintains moisture, elasticity and healthy skin suffers the destructive effects of inflammation, glycation and oxidative stress.

Science in Skincare: Supplamine

  • Supplamine prevents skin damage in two distinct ways: by preventing the development of toxic sugars and neutralizing the toxic sugars in our systems.
  • MEG 21 products with Supplamine: prevent skin aging and wrinkling; stop glycation, inflammation, and oxidative stress; boost collagen production; target toxic sugars in skin; and even tone skin and reverse the appearance of aging skin.
  • MEG 21 with patented age-reversing Supplamine® attacks each of these conditions resulting in major skin improvement.


9 Doctor-Run, Independent Clinical Trials

Toxic Sugars detected in skin as we age:
  • 23 Year Old 15% 15%
  • 49 Year Old 35% 35%
  • 69 Year Old 75% 75%
Increase in skin health after 4 weeks use:
  • Firmness by Ballistomoter 22% 22%
  • Moisture by Impedence Meter 42% 42%
  • Smoothness by Expert Grader 43% 43%
  • Smoothness by Image Analysis 37% 37%
Skin Improvement over 4 weeks: Hand
  • Reduced Crepiness 24% 24%
  • Reduced Roughness 45% 45%
  • Increased Moisturization 143% 143%

Clinical Trials

Rigorous scientific research provides the proof and efficacy of our patented, ingredient, Supplamine, found only in MEG 21 products.

Many trials and tests of MEG 21 products, including double-blind studies and those using placebos, comparative products and consumer insights, have been mounted by independent laboratories. We are happy to share the information with you.

Download our complete clinical trials PDF here.


Skin improvement over 4 weeks: Decollete
  • Reduced Crepinesss 27% 27%
  • Reduced Roughness 38% 38%
  • Increased Moisturization 25% 25%

Four-Week Ophthalmologic Study

MEG 21 Bright and Firm Eye Treatment

Ophthalmologic Safety-in-Use and Consumer-Perception Study

MEG 21 Bright and Firm Eye Treatment

Download the new clinical trial results

  • Less visible wrinkles/fine lines around eyes 97% 97%
  • No irritation 100% 100%
  • Made their skin feel firmer 100% 100%
  • Better than previously used eye products 100% 100%
  • Increase moisture of skin around eyes 100% 100%

MEG 21 is one of the few anti-aging products that delivers what it claims and has the research available to stand behind them.

Dr. Georgeann Dau

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© 2021 MEG 21 Skincare.  All rights reserved. 

MEG products are made in the U.S.A.
A portion of the proceeds from their sales goes to fund cancer research.