
Images are for illustration purposes only.
Clinical results, measured on skin
Each participant was measured against their own starting point.
In an 8-week open-label study of an original MEG 21 Supplamine® formula, conducted by a contract research organisation.
Individual results may vary.
Before and after
Before and after photos of skin cared for with MEG 21.
Before
After 28 daysNeck
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Before
After 28 daysNeck, side view
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Before
After 28 daysSmile line
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Before
After 28 daysCrow's feet
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Before
After 28 daysEye area
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Before
After 28 daysForehead
Shop Face Treatment →Individual results may vary.
What customers say they feel
In their own words, from reviews on meg21.com.
Removes the tight feeling of undernourished skin and reduces wrinkles. My skin feels plump. Of all my skin products, this is the one I would greatly miss and consider my most essential!
Have used Meg 21 products for years, but just found it online. Ordered this for my face. Love the texture and the hydrated feeling. I feel as though my skin actually drinks this product in. I would highly recommend it!
Considering the largest organ in our body is our skin, it is imperative to treat it well. I have been using MEG 21 for years & it is my Go To nightly moisturizer! My skin feels amazing - Yes, smooth & radiant!!!
I have loved this product for years. I’m delighted for its return. It smooths, softens, and keeps me looking radiant.
I have seen great results when using MEG 21. Goes on smooth and keeps my face moist and supple.
Simply smooth & creamy. Doesn’t have a fragrance and doesn’t make my skin breakout.
What study participants reported
Self-reported at week 8.
What physicians say
In their words.
I was introduced to MEG 21 over 20 years ago. I was dazzled by the science but fell in love with how great it works. This has been my go-to product for myself, my family, and my patients.

MEG 21 offers effective moisturization, addresses skin firmness and reduces fine lines and wrinkles in as little as four weeks.

What I love about MEG 21 is that it actually works — thanks to Supplamine®, their powerful, science-backed secret weapon. It does the heavy lifting, delivering real, visible improvements with smoother skin. No hype — just healthier, more resilient skin you can truly see and feel.

MEG 21 products are by far the best topical treatments for deep moisturizing and anti-aging effects that I have found. When I recommend MEG 21, I speak from both science and personal experience. It makes skin supple — less wrinkled, less dry, less 'hard.'

Want the science behind it?
Try MEG 21 with the Discovery Kit
Five travel sizes of the MEG 21 anti-glycation range in a custom cosmetic bag: the serum, two treatments, the eye treatment and the mineral SPF. The whole routine, before you commit to full sizes.
Shop the Discovery Kit — $30*Disclaimer: The information presented on website is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. *Clinical References: References to clinical studies relate to the evaluation of ingredients or product formulations for visible skin appearance and condition. *Supplamine® is a patented compound developed for cosmetic use. Statements regarding its effects are based on in vitro studies, ingredient data, and third-party clinical evaluations of finished skincare products. *No Medical Claims: MEG 21 products are cosmetic and not drugs. They are not intended to modify the structure or function of the skin or body. *Individual Results May Vary.
