GLYCATION: The Hidden Culprit Behind Premature Aging

Patented Supplamine® helps block sugar-induced protein cross-linking that stiffens and dulls skin

Meg 21 supports firmer, more resilient texture by preserving collagen and elastin integrity

Clinically tested to help diminish the appearance of fine lines and restore youthful radiance

Anti-glycation authority

NINE CLINICAL STUDIES

MEG 21 with Supplamine® stands at the forefront of scientific innovation in skincare, addressing one of the most critical yet overlooked processes of skin aging: glycation.

Originating from cancer and diabetes research at the Fox Chase Cancer Center, Supplamine® has been rigorously tested and proven effective through multiple clinical studies over the past 20 years. Our unique approach combines cutting-edge science with practical skincare solutions, making MEG 21 the most scientifically advanced anti-glycation skincare brand on the market.

Shop now

Scientific Background

MEG 21 with Supplamine® began as a tangent while researching new treatments for diabetes- related complications. While the research focused on treating and preventing kidney disease and blindness in diabetic patients, Dr. Annette M. Tobia, Ph.D., realized that, when topically applied, many of
these same compounds used to treat diabetics could also be used to treat and prevent visible signs of aging in the skin.

After more than seven independent trials showed remarkable results, MEG 21 with Supplamine® was launched as an innovative professional skincare line.

Cellular Studies Show
Toxic Sugars Damage Collagen in Skin

Laboratory research shows that Supplamine® reduces toxic sugars through its dual-action formula:

  1. Helps lower inflammation linked to glycation
  2. Naturally neutralizes harmful sugars from carb- and fat-rich diets

By targeting these root causes, MEG 21 visibly reduces the appearance of fine lines, wrinkles, sagging, and dryness—often in as little as 28 days.

Shop now

Meg 21 is a comprehensive skincare line that revolves around the theory of glycation—a biological process of glucose
(sugar) binding to proteins and lipids in the skin, causing premature aging in the skin.

Shop now