There is skincare.

Then, there is scientific skincare.

We have been pioneers of professional-grade anti-glycation skincare since 1996. With over 25 years of relentless innovation, we adhere to the highest standards of scientific excellence, constantly pushing the boundaries to deliver revolutionary skincare solutions.

the anti-glycation authority.

MEG21 scientists pioneered the research on skin glycation and patented a compound, Supplamine, clinically-proven to fight glycation in the skin. 9 INDEPENDENT CLINICAL STUDIES - 150 SUBJECTS TESTED - US PATENT GRANTED.

15 PATENTS +

NINE INDEPENDENT CLINICAL STUDIES

MEG 21 with Supplamine® stands at the forefront of scientific innovation in skincare, addressing one of the most critical yet overlooked processes of skin aging: glycation.

Originating from cancer and diabetes research at the Fox Chase Cancer Center, Supplamine® has been rigorously tested and proven effective through multiple clinical studies over the past 20 years. Our unique approach combines cutting-edge science with practical skincare solutions, making MEG 21 the most scientifically advanced anti-glycation skincare brand on the market.

One anti-inflammatory approach to beauty

Supplamine®: The INNOVATIVE Anti-Glycation Solution

Supplamine® is a proprietary and patented ingredient in MEG 21 products, specifically designed to combat glycation and its detrimental effects on the skin. The formula combines two powerful compounds:

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  • Meglumine

    An amino sugar that acts as an enzyme inhibitor. Meglumine attracts the F3K enzyme, which produces toxic sugars, preventing these sugars from being made and thereby blocking the inflammation process.

  • Arginine

    A natural amino acid that neutralizes already-produced toxic sugars by binding to them. Arginine also enhances antioxidant activity, supports collagen production, improves hydration, and protects the skin barrier.

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dual-acting supplamine®

Supplamine® operates through a dual-acting mechanism:

Reduces Inflammation: Associated with glycation, reducing skin damage.

Inactivates Toxic Sugars: Neutralizes sugars from carbohydrate and fat-rich diets, reducing the appearance of fine lines, wrinkles, sagging, and dryness.

MEG 21 with Supplamine® represents a breakthrough in anti-glycation skincare. Backed by 20 years of research, 15 patents and patents pending, and numerous clinical studies, our products deliver scientifically validated results. Supplamine® addresses the root causes of skin aging, offering a comprehensive solution that combines innovation, scientific integrity, and proven efficacy.

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