Meet Your Daily Skincare Heroes
Your three essential steps to a smoother, brighter complexion.
Real People, Real Results | After 8 weeks*


Before
After


Before
After


Before
After


Before
After


Before
After


Before
After
*Individual results may vary.
GLYCATION: The Hidden Culprit Behind Premature Aging

Patented Supplamine® helps block sugar-induced protein cross-linking that stiffens and dulls skin

Meg 21 supports firmer, more resilient texture by preserving collagen and elastin integrity

Clinically tested to help diminish the appearance of fine lines and restore youthful radiance

Supplamine®:
Patented
Medical-Grade
Anti-Aging Innovation
Discover The Science
FROM CANCER RESEARCH TO SKINCARE BREAKTHROUGH
MEG 21 with Supplamine® began with scientific research at Fox Chase Cancer Center, where scientists were studying sugar-related damage in cancer and diabetes. They discovered it was possible to reduce the formation of AGEs — harmful compounds that accelerate aging.
Dr. Annette M. Tobia, Ph.D., saw its potential beyond medicine. Working with Fox Chase researchers, she helped develop and test the science for skincare — leading to the creation of Supplamine®, the patented compound at the heart of MEG 21.

Bestsellers
From the blog
Discover our latest articles and insights

From Metformin to Supplamine®: The Science of Anti-Glycation Skincare
In recent years, the medical and scientific communities have shown renewed interest in theaging process...
Read more

The Power of Anti-Glycation End (A.G.E.) Skincare: What It Is and Why You Need It
Anti-Glycation End (A.G.E.) skincare—a groundbreaking approach to skincare that addresses one of the lesser-known culprits of skin aging: glycation. In this article, we’ll break down what glycation is, why A.G.E. products are beneficial, and how our line at Meg 21 can help you maintain youthful, radiant skin.
Read more

Supplamine® : Novel Science in Skincare
Supplamine® prevents skin damage in two distinct ways, by: preventing the development of toxic sugars and neutralizing the toxic sugars in our skin from the foods we eat.
Read more

Sugar? No Thanks! The Truth About Glycation
“Sugar and spice and everything nice” is what little girls were said to be made of, which is a lot better than the “snips and snails” that was the stuff of little boys. As a young girl, having sugar as a basic building block may seem fantastic, but when it comes to skin health and aging it is anything but.
Read more
Patented Supplamine®
Clinically Tested
Anti-Glycation Power
A.G.E. Skincare