Antioxidant Boost Serum

Shield + Power Anti-Oxidant Boost Serum

  • Supplamine®
  • Antioxidants
  • Lightweight
  • Radiant Look
$95.001 oz / 30 g
4.8 9 reviews

This lightweight, silky serum combines Supplamine®, Indian Gooseberry, and Grape Seed Extract to help combat visible signs of glycation, oxidative stress, and environmental damage.
It’s formulated to support skin’s defense against free radical exposure and visible photodamage, while helping improve the look of uneven tone, fine lines, and dullness — for a smoother, more radiant-looking complexion.

 (1 oz / 30 g)

Physician-dispensed
Supplamine® anti-glycation technology

Apply 2 to 3 drops to clean skin and gently press into face and neck.

Follow with your MEG 21 eye and face treatment, and finish with SPF in the morning.

All skin types.

For dull-looking or uneven-looking skin, and for anyone who wants extra antioxidant support against everyday environmental stress. Light and silky, it layers easily under your treatment cream.

Water, Glycerin, Butylene Glycol, Phyllanthus Emblica Fruit Extract, Symphytum Officinale Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Arginine, Hydrogenated Polydecene, Methylglucamine HCl, Polyacrylamide, C13-14 Isoparaffin, Propylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dimethicone, Glucosyl Hesperidin, Oenothera Biennis Oil, Triethanolamine, Laureth-7, Parfum, Tocopheryl Nicotinate, Disodium EDTA, Hydrolyzed Soy Protein, Methylparaben, Propylparaben, Butylphenyl Methylpropional, Citronellol, Linalool

How it works in the skin

Supplamine® is the heart of every MEG 21 formula, this original one included. It helps interrupt glycation early, where sugars bond to collagen and elastin.

  • Supplamine® at the coreOur signature anti-glycation complex.
  • The original formulaThe MEG 21 customers have used for years.
Explore the science

Try the new formula

MEG 21 Advanced Defense Serum SP-IV Complex bottle

New formula

Advanced Defense Serum

The same MEG 21 science, updated in our newest formula.

$175.00

View

Trusted by physicians

Developed by Dr. Annette Tobia, PhD, and dispensed by physicians who trust it with their patients.

  • Physician-dispensedOffered in medical practices.
  • Complements your treatmentsUse between visits, once your provider says your skin is ready.
For professionals
Dr. Betsy A.B. Greenleaf, DO
Dr. Betsy A.B. Greenleaf, DOFACOOG, FACOG, FPMRS, FAAOPM, MBA
I was dazzled by the science but fell in love with how great it works. This has been my go-to product for myself, my family, and my patients.
Dr. Adrian Manjarrez-Cortez, MD
Dr. Adrian Manjarrez-Cortez, MDPlastic Surgery
MEG 21 offers effective moisturization, addresses skin firmness and reduces fine lines and wrinkles…
Dr. Kenneth Redcross, MD
Dr. Kenneth Redcross, MDInternal Medicine
What I love about MEG 21 is that it actually works — thanks to Supplamine®, their powerful, science-backed secret weapon.
Dr. Alice McKee, MD
Dr. Alice McKee, MDFamily Medicine
When I recommend MEG 21, I speak from both science and personal experience. It makes skin supple — less wrinkled, less dry, less 'hard.'

Try MEG 21 with the Discovery Kit

Five travel sizes of the MEG 21 anti-glycation range in a custom cosmetic bag: the serum, two treatments, the eye treatment and the mineral SPF. The whole routine, before you commit to full sizes.

Shop the Discovery Kit — $30