Anti-Glycation Eye Cream

Bright & Firm Eye Treatment

Supplamine®
Brightening
Firming
Delicate Eye Area

$85.000.5 oz / 15 g

4.6 66 reviews

This powerful under-eye anti-aging treatment powered by Supplamine® firms, brightens, and soothes the delicate eye area. Clinically proven to diminish the appearance of fine lines, crow's feet, puffiness, and wrinkles around and under the eyes while gradually reducing the appearance of dark circles.

In an ophthalmologist-conducted study, its efficacy was proven.
Non-irritating for even sensitive eyes and contact lens wearers.

(0.5 oz)

Physician-dispensed

Supplamine® anti-glycation technology

Morning and night, gently pat a small amount around the orbital bone with your ring finger. Avoid direct contact with the eye.

Follow with your face treatment, and finish with SPF in the morning.

All skin types, including sensitive eyes and contact lens wearers.

For anyone who wants the eye area to look brighter and firmer, with softer-looking fine lines, puffiness and dark circles.

Water, Cyclopentasiloxane, Pentylene Glycol, Caprylic/Capric Triglyceride, Arginine HCl, Methylglucamine HCl, Ethylhexyl Palmitate, Lecithin, Aminopropyl Dimethicone, Steareth-21, Cetearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Argilla (Magnesium Aluminum Silicate), Polyamide-5, PEG-100 Stearate, PEG-40 Hydrogenated Castor Oil, Isohexadecane, Ceteareth-20, Sodium Benzoate, Butylene Glycol, Pfaffia Paniculata Root Extract, Ptychopetalum Olacoides Bark/Stem Extract, Batyl Alcohol, Butyrospermum Parkii (Shea) Butter, Palmitoyl Hydrolyzed Wheat Protein, Lilium Candidum Flower Extract, Chlorphenesin, Steareth-2, 1,2-Hexanediol, Caprylyl Glycol, Potassium Sorbate, Polysorbate 60, Titanium Dioxide, Xanthan Gum, Parfum, Disodium EDTA, Sorbitan Isostearate, BHT, Limonene, Citral, Geraniol

Pair it with these for a full morning-to-night routine.

What users reported

Participants used the eye treatment for 4 weeks and rated the change they saw around their own eyes.

4-week study35 participants, original eye formula.
Self-reported resultsWhat participants saw and felt.
The original formulaThis is the formula the study used.

Explore the science

100%felt the eye area was firmerat 4 weeks · Self-reported

97%felt fine lines looked less visibleat 4 weeks · Self-reported

89%felt dark circles looked lighterat 4 weeks · Self-reported

Consumer-perception study of the original MEG 21 eye formula: 35 participants, 4 weeks. Results are self-reported.

Individual results may vary.

How it works in the skin

Supplamine® is the heart of every MEG 21 formula, this original one included. It helps interrupt glycation early, where sugars bond to collagen and elastin.

Supplamine® at the coreOur signature anti-glycation complex.
The original formulaThe MEG 21 customers have used for years.

Explore the science

Our anti-glycation complex intercepting sugar by-products above collagen fibres

Supplamine®Our anti-glycation technologyHelps interrupt glycation early, when sugars bond to collagen and elastin.Learn more

Images are for illustration purposes only.

Trusted by physicians

Developed by Dr. Annette Tobia, PhD, and dispensed by physicians who trust it with their patients.

Physician-dispensedOffered in medical practices.
Complements your treatmentsUse between visits, once your provider says your skin is ready.

For professionals

**Dr. Betsy A.B. Greenleaf, DO**FACOOG, FACOG, FPMRS, FAAOPM, MBA
I was dazzled by the science but fell in love with how great it works. This has been my go-to product for myself, my family, and my patients.

**Dr. Adrian Manjarrez-Cortez, MD**Plastic Surgery
MEG 21 offers effective moisturization, addresses skin firmness and reduces fine lines and wrinkles…

**Dr. Kenneth Redcross, MD**Internal Medicine
What I love about MEG 21 is that it actually works — thanks to Supplamine®, their powerful, science-backed secret weapon.

**Dr. Alice McKee, MD**Family Medicine
When I recommend MEG 21, I speak from both science and personal experience. It makes skin supple — less wrinkled, less dry, less 'hard.'

Try MEG 21 with the Discovery Kit

Five travel sizes of the MEG 21 anti-glycation range in a custom cosmetic bag: the serum, two treatments, the eye treatment and the mineral SPF. The whole routine, before you commit to full sizes.

Shop the Discovery Kit — $30