Peptide Anti-Glycation Eye Treatment

Peptide Bright & Firm Eye Treatment

  • Supplamine®
  • Peptides
  • Caffeine
  • Bakuchiol
$85.000.5 oz / 15 g

A peptide eye treatment built for the thinnest skin on the face. Supplamine® anti-glycation technology with a three-peptide complex, caffeine, niacinamide, Vitamin C, and bakuchiol.

Lightweight and gentle enough for the eye area, morning and night.

Physician-dispensed
Supplamine® anti-glycation technology

Apply AM and PM around the orbital bone using your ring finger, after serum and before moisturizer.

A small amount is sufficient. Avoid direct contact with the eye.

All skin types. Built for anyone 30 and over concerned with fine lines, dark circles, or puffiness around the eyes.

The easiest place to start with MEG 21, and the natural partner to Advanced Defense Serum since both carry the same peptide family.

Water (Aqua), Glycerin, Aloe Barbadensis Leaf Juice, Aloe Barbadensis Extract, Butylene Glycol, Cetearyl Alcohol, Cocos Nucifera (Coconut) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Polysorbate 60, Niacinamide, Arginine HCl, Methylglucamine HCl, Hamamelis Virginiana (Witch Hazel) Water, Persea Gratissima (Avocado) Oil, Vitis Vinifera (Grape) Seed Oil, Stearic Acid, Sodium Ascorbyl Phosphate, Caffeine, Sodium Polyacrylate, Polysorbate 20, Phenoxyethanol, Salix Alba (Willow) Bark Extract, Hydrolyzed Silk, Melia Azadirachta Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Tetrasodium Glutamate Diacetate, Xanthan Gum, Alcohol, Hydrolyzed Rice Bran Protein, Oxidoreductases, Lecithin, Bakuchiol, Carbomer, Pentylene Glycol, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Glycine Soja (Soybean) Protein, Palmitoyl Tripeptide-5, Sodium Hyaluronate, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Potassium Sorbate, Sodium Benzoate, Sodium Hydroxide, Citric Acid.

How it works in the skin

Supplamine® is the heart of MEG 21. Around the eyes, where skin is thinnest, it works alongside peptides and hydration made for this delicate area.

  • Supplamine® at the coreOur signature anti-glycation complex.
  • Made for the eye areaFor the thinnest skin on the face.
  • Same peptide familyAs our Advanced Defense Serum.
Explore the science

What's inside

Supplamine® leads the way, with peptides, caffeine, brightening vitamins and a gentle retinol alternative for the delicate eye area.

  • Supplamine® at the coreOur signature complex, in every formula.
  • A gentle retinol alternativeBakuchiol, suited to the eye area.
  • Morning and nightApply around the orbital bone.
Explore the science

Images are for illustration purposes only.

Loved by MEG 21 customers

Supplamine® is at the heart of every MEG 21 formula. Here is what long-time customers say about theirs.

  • Loyal for yearsMany have used MEG 21 for years.
  • Recommended by professionalsOften first suggested by their esthetician or dermatologist.
Read more stories
My skin care person turned me on to this product. I really think the attack on glycation is a strength of this product. I highly recommend it.
Amy H.On Décolleté Treatment Advanced Formula
I discovered Meg 21 many years ago through my dermatologist. I have tried so many other brands....and there are still others out there that are terrific....but Meg 21 gets the blue ribbon!!! Moisture without the greasiness. Love this product!!
OliviaOn Smooth Radiance Face Treatment
I have been using this for at least 5 years and I absolutely love this product. My face does not dry out and my skin looks fresh at the end of the day.
BrittanyOn Smooth Radiance Face Treatment

Trusted by physicians

Developed by Dr. Annette Tobia, PhD, and dispensed by physicians who trust it with their patients.

  • Physician-dispensedOffered in medical practices.
  • Complements your treatmentsUse between visits, once your provider says your skin is ready.
For professionals
Dr. Betsy A.B. Greenleaf, DO
Dr. Betsy A.B. Greenleaf, DOFACOOG, FACOG, FPMRS, FAAOPM, MBA
I was dazzled by the science but fell in love with how great it works. This has been my go-to product for myself, my family, and my patients.
Dr. Adrian Manjarrez-Cortez, MD
Dr. Adrian Manjarrez-Cortez, MDPlastic Surgery
MEG 21 offers effective moisturization, addresses skin firmness and reduces fine lines and wrinkles…
Dr. Kenneth Redcross, MD
Dr. Kenneth Redcross, MDInternal Medicine
What I love about MEG 21 is that it actually works — thanks to Supplamine®, their powerful, science-backed secret weapon.
Dr. Alice McKee, MD
Dr. Alice McKee, MDFamily Medicine
When I recommend MEG 21, I speak from both science and personal experience. It makes skin supple — less wrinkled, less dry, less 'hard.'

Complete your routine

Loved it for your eyes? These complete the routine around it.

  • The Peptide DuoAdvanced Defense Serum: the full-face version of the same peptides.
  • Daily SPFThe eye area needs sun protection every morning.
Shop the routine
Advanced Defense SerumThe Peptide DuoThe full-face version. Same peptide family.
$175.00
Smooth Radiance Face TreatmentNext stepThe daily treatment step. Apply after this eye treatment.
$130.00
Daily Mineral Shield SPF 30 TintedEvery morningThis treatment offers no sun protection. Finish with SPF.
$60.00

Try MEG 21 with the Discovery Kit

Five travel sizes of the MEG 21 anti-glycation range in a custom cosmetic bag: the serum, two treatments, the eye treatment and the mineral SPF. The whole routine, before you commit to full sizes.

Shop the Discovery Kit — $30