Peptide Anti-Glycation Eye Treatment
Peptide Bright & Firm Eye Treatment
- Supplamine®
- Peptides
- Caffeine
- Bakuchiol
A peptide eye treatment built for the thinnest skin on the face. Supplamine® anti-glycation technology with a three-peptide complex, caffeine, niacinamide, Vitamin C, and bakuchiol.
Lightweight and gentle enough for the eye area, morning and night.
Water (Aqua), Glycerin, Aloe Barbadensis Leaf Juice, Aloe Barbadensis Extract, Butylene Glycol, Cetearyl Alcohol, Cocos Nucifera (Coconut) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Polysorbate 60, Niacinamide, Arginine HCl, Methylglucamine HCl, Hamamelis Virginiana (Witch Hazel) Water, Persea Gratissima (Avocado) Oil, Vitis Vinifera (Grape) Seed Oil, Stearic Acid, Sodium Ascorbyl Phosphate, Caffeine, Sodium Polyacrylate, Polysorbate 20, Phenoxyethanol, Salix Alba (Willow) Bark Extract, Hydrolyzed Silk, Melia Azadirachta Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Tetrasodium Glutamate Diacetate, Xanthan Gum, Alcohol, Hydrolyzed Rice Bran Protein, Oxidoreductases, Lecithin, Bakuchiol, Carbomer, Pentylene Glycol, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Glycine Soja (Soybean) Protein, Palmitoyl Tripeptide-5, Sodium Hyaluronate, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Potassium Sorbate, Sodium Benzoate, Sodium Hydroxide, Citric Acid.
Pair it with these for a full morning-to-night routine.
How it works in the skin
Supplamine® is the heart of MEG 21. Around the eyes, where skin is thinnest, it works alongside peptides and hydration made for this delicate area.
- Supplamine® at the coreOur signature anti-glycation complex.
- Made for the eye areaFor the thinnest skin on the face.
- Same peptide familyAs our Advanced Defense Serum.
PeptidesFirmer-looking skinSupport the look of firmer skin.Learn more
Hyaluronic acidLasting hydrationDraws in and holds moisture.Learn more Images are for illustration purposes only.
What's inside
Supplamine® leads the way, with peptides, caffeine, brightening vitamins and a gentle retinol alternative for the delicate eye area.
- Supplamine® at the coreOur signature complex, in every formula.
- A gentle retinol alternativeBakuchiol, suited to the eye area.
- Morning and nightApply around the orbital bone.
Multi-Peptide Complex
Firmer, smoother-looking skin
Peptides are short chains of amino acids, the components that make up skin proteins. Our formulas pair signal peptides such as palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1 to help support skin that looks firmer and smoother, with a more refined texture.
Learn more
Caffeine
Refreshed eye appearance
Caffeine is a well-known energizing ingredient in eye care. Applied to the skin, it helps reduce the look of puffiness and dark circles, so the eye area appears brighter, smoother and more rested.
Learn more
Bakuchiol
Smoother-looking skin
Bakuchiol is a plant-based compound from the seeds of the babchi plant, often called a natural alternative to retinol. It helps skin look smoother and firmer and helps soften the look of fine lines, while staying gentle enough for the delicate eye area.
Learn more
Niacinamide
Even-looking tone
Niacinamide, a form of vitamin B3, is one of skincare's most versatile ingredients. It helps even the look of skin tone, supports the skin barrier and helps refine the look of pores, making it a valuable partner in our Eye Treatment.
Learn more
Vitamin C Derivative
Antioxidant brightening support
Sodium ascorbyl phosphate is a stable, water-soluble form of vitamin C. It helps defend skin against environmental stressors and helps brighten the look of dull skin, without the sting some pure vitamin C forms can cause.
Learn more
Images are for illustration purposes only.
Loved by MEG 21 customers
Supplamine® is at the heart of every MEG 21 formula. Here is what long-time customers say about theirs.
- Loyal for yearsMany have used MEG 21 for years.
- Recommended by professionalsOften first suggested by their esthetician or dermatologist.
Trusted by physicians
Developed by Dr. Annette Tobia, PhD, and dispensed by physicians who trust it with their patients.
- Physician-dispensedOffered in medical practices.
- Complements your treatmentsUse between visits, once your provider says your skin is ready.

I was dazzled by the science but fell in love with how great it works. This has been my go-to product for myself, my family, and my patients.

MEG 21 offers effective moisturization, addresses skin firmness and reduces fine lines and wrinkles…

What I love about MEG 21 is that it actually works — thanks to Supplamine®, their powerful, science-backed secret weapon.

When I recommend MEG 21, I speak from both science and personal experience. It makes skin supple — less wrinkled, less dry, less 'hard.'
Complete your routine
Loved it for your eyes? These complete the routine around it.
- The Peptide DuoAdvanced Defense Serum: the full-face version of the same peptides.
- Daily SPFThe eye area needs sun protection every morning.
Try MEG 21 with the Discovery Kit
Five travel sizes of the MEG 21 anti-glycation range in a custom cosmetic bag: the serum, two treatments, the eye treatment and the mineral SPF. The whole routine, before you commit to full sizes.
Shop the Discovery Kit — $30









